Across the street at Danny’s Skylight Room, the amaz­ing Annie Hughes opened her latest show, “In My Life,” last Friday. I ran out of adjectives years ago trying to describe her show-stopping coloratura work and the sheer beauty of her voice. Like Barbara Cook, she is a soprano who can sing lyrical legit pieces yet have fun with jazzier arrangements. Accompanied by musical director Daryl Kojak, Hughes offers everything from the Beatles (“Seventeen”) to Jason Robert Brown (“Alice’s Song”).

She was especially expressive with a heartfelt pairing of Eden Ahbez’ “Nature Boy” and John Latouche and Jerome Moross’ “Lazy Afternoon” (from “The Golden Apple”). But Hughes really excels at musical comedy. She was joined by a special guest, handsome baritone Rob Langeder, and they made a dynamite duo as they performed comic songs by Linda Wallem and Peter Tolan. The night’s highlight was “Literate Broadway,” which included a musical of “Dick and Jane” as if it had been written by Stephen Sondheim. It was wacky and wonderful - and that describes Hughes, too. She’s playing Fridays at 9:15 pm through November at Danny’s.